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Symbol Name ID |
Sp8
trans-acting transcription factor 8 MGI:2443471 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | nervous system phenotype |
increased neuron apoptosis |
abnormal neuronal precursor proliferation |
incomplete caudal neuropore closure |
incomplete rostral neuropore closure |
spina bifida |
abnormal forebrain development |
abnormal telencephalon development |
abnormal cortical plate morphology |
thin cortical plate |
abnormal olfactory bulb development |
holoprosencephaly |
forebrain hypoplasia |
abnormal lateral ventricle morphology |
abnormal brain internal capsule morphology |
abnormal basal ganglion morphology |
abnormal telencephalon morphology |
abnormal olfactory bulb layer morphology |
abnormal olfactory bulb external plexiform layer morphology |
abnormal olfactory bulb glomerular layer morphology |
abnormal olfactory bulb internal plexiform layer morphology |
small olfactory bulb |
telencephalon hypoplasia |
absent cerebellum |
exencephaly |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||
| Sp8tm1Aman/Sp8tm1Aman | ||||||||||||||||||||||||||
| Sp8tm1Smb/Sp8tm1Smb | ||||||||||||||||||||||||||
| Sp8tm2.1Aman/Sp8tm2.1Aman Foxg1tm1(cre)Skm/Foxg1+ (conditional) |
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| Sp8tm2Smb/Sp8tm2Smb Tg(mI56i-cre,EGFP)1Kc/? (conditional) |
* | |||||||||||||||||||||||||
| Sp8tm1Smb/Sp8tm2Smb Foxg1tm1(cre)Skm/Foxg1+ (conditional) |
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| Sp8tm1Smb/Sp8tm2Smb Pax3tm1(cre)Joe/Pax3+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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